Newton's law of gravitation, general relativity, and the standard model of particle physics may be subject to modification in the future.
But as I thought about this, the physical constants of the universe are probably real tangible elements of reality, which humans did not invent as part of a constructed mathematical language.
The gravitational constant and Planck's constant were discovered, not invented. They appear to be a tangible element of reality underlying the universe, and are only known by experimental measurement; they cannot be derived from first principles.