Here are some accounts I found about use and effect:
Taken in high doses, nutmeg can be quite intoxicating, partly because it's similar in chemical makeup to MDMA. Nutmeg causes symptoms such as stupor, drowsiness, delirium and sleep. Many prison inmates have known about it and used it for years, which is why most prisons have banned the use of this spice! About 14 grams (two tablespoons) taken by mouth cause a rather unpleasant, dreamlike "trip". Other symptoms include a rapid heartbeat, dry mouth, and thirst. Agitation, apprehension, and a sense of impending doom may last about 12 hours, with a sense of unreality persisting for several days. Nutmeg contains five to 15 per cent myrista oil, which is responsible for the physical effects. About four per cent is Myristicin, which is structurally similar to mescaline. (Mace, the exterior covering of the Nutmeg seed, also contains the hallucinogenic compound myristicin). Elemicin is another potent psychoactive ingredient in nutmeg. Similar to SSRI antidepressants such as Prozac, Myristicin blocks the release of serotonin from brain neurones. Scientists believe that once the substance enters the body it's converted to methylenedioxymethamphetamine (MDMA) -- ecstasy.
I guess you could call me a nutmeg person. I have taken it around 10 or 11 times in the last year and love it. At first, I only take about a tablespoon or so at about 11:30 am. then i wait till about 6 or 7 pm and the drug starts to kick in. The first few times you try it, the effects are a little like being drunk or "almost" high on weed. Then after about 3 or 4 times using it you will start to be able to trip hard, ive even seen shit. Now when i take it, it only takes about 3 to 4 hours to kick in and i trip like a motherfucker, i now prefer it over weed even. Only problem is that you have to plan yoru day around it. Dont take it past 1:30 pm and be prepared to feel it for a little bit the next day. peace.