Assembly Theory

Mott, I love you man, but this is just seriously fucked up codswallop. I just can't believe that Nature would even give it the time of day.

Assembly Theory is Ontogenetic Depth relabeled, nothing more, and is just as useless

How exactly does this dreck, Assembly Theory explain and quantify selection and evolution, get published in Nature?

assembly-theory-abstract.jpg

It’s a stunningly bad paper to be published in such a prestigious journal. Let’s dissect that abstract, shall we?

Scientists have grappled with reconciling biological evolution1,2 with the immutable laws of the Universe defined by physics.

This makes no sense. Evolutionary biologists have not had any problem with physical laws — it has always been assumed, as far as I know, that biology fits within the framework of chemistry and physics. What grappling? Have biologists been proposing theories that violate physics, and they didn’t tell me?

The citations to back up that outré claim are Stuart Kauffman, who can get a little weird but not that weird, and Ryan Gregory, whose papers I’ve used in class, and is probably a bit annoyed at being told his work supports that ridiculous claim.

These laws underpin life’s origin, evolution and the development of human culture and technology, yet they do not predict the emergence of these phenomena.

Sure. Emergent properties exist. We know you can’t simply derive all of biology from Ideal Gas Law. So far, nothing new.

Evolutionary theory explains why some things exist and others do not through the lens of selection.

Uh-oh. Just selection? Tell me you know nothing of evolutionary biology without saying you don’t know anything about evolutionary biology.

To comprehend how diverse, open-ended forms can emerge from physics without an inherent design blueprint, a new approach to understanding and quantifying selection is necessary3,4,5.

Here it comes, more bad theorizing. It is implicit in evolution that there is no “inherent design blueprint,” so where did these authors get the idea that design was a reasonable alternative? They don’t say. This is simply another imaginary controversy they’ve invented to make their theory look more powerful.

We don’t need a "new approach" to selection. To support that, they cite Charles Darwin (???) and Sean B. Carroll, and a fellow named Steven Frank, whose work I’m unfamiliar with. A quick search shows that he applies “evolutionary principles to the biochemistry of microbial metabolism,” which doesn’t sound foreign to standard biology, although he does throw the word “design” around a lot.

But here we go:

We present assembly theory (AT) as a framework that does not alter the laws of physics, but redefines the concept of an ‘object’ on which these laws act. AT conceptualizes objects not as point particles, but as entities defined by their possible formation histories. This allows objects to show evidence of selection, within well-defined boundaries of individuals or selected units.

Again, what biological theory has ever been proposed that alters the laws of physics? They keep touting this as a key feature of their model, that it doesn’t break physics, but no credible theory does. This talk of "formation histories" is nothing revolutionary, history and contingency are already important concepts in biology. Are they really going to somehow quantify “assembly”? They’re going to try.

We introduce a measure called assembly (A), capturing the degree of causation required to produce a given ensemble of objects. This approach enables us to incorporate novelty generation and selection into the physics of complex objects. It explains how these objects can be characterized through a forward dynamical process considering their assembly.

I’ve heard this all before, somewhere. A new term invented, a claim of a novel measure of the complexity of a pathway, a shiny new parameter with no clue how to actually measure it? This is just ontogenetic depth! Paul Nelson should be proud that his bad idea has now been enshrined in the pages of Nature, under a new label. I did a quick check: Nelson is not cited in the paper. Sorry, Paul.

Here is all "assembly theory" is: You count the number of steps it takes to build an organic something, and presto, you’ve got a number "A" that tells you how difficult it was to evolve that something. That’s it. Biology is revolutionized and reconciled with physics. It’s just that stupid.

Read more: https://freethoughtblogs.com/pharyn...elabeled-nothing-more-and-is-just-as-useless/
 
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I recall as a kid my dad, who ran a lab at Monsanto, being excited about the new gizmo they had just gotten -- this one. One of the things he was proud of was their partnership with arson investigators. They could use it to identify possible accelerants.

That you could. Down to the parts per billion range. Some high sensitivity models can detect at the ppt range.
 
backward looking troglodytic nonsense, trying to shit on god.

Actually you’re right. It is backward looking. Having said that you can learn a lot about how something is assembled by breaking it down to its component parts.

Hey! I thought you worshiped Chthulu?!
 
Mott, I love you man, but this is just seriously fucked up codswallop. I just can't believe that Nature would even give it the time of day.

Assembly Theory is Ontogenetic Depth relabeled, nothing more, and is just as useless

How exactly does this dreck, Assembly Theory explain and quantify selection and evolution, get published in Nature?

View attachment 25654

It’s a stunningly bad paper to be published in such a prestigious journal. Let’s dissect that abstract, shall we?

Scientists have grappled with reconciling biological evolution1,2 with the immutable laws of the Universe defined by physics.

This makes no sense. Evolutionary biologists have not had any problem with physical laws — it has always been assumed, as far as I know, that biology fits within the framework of chemistry and physics. What grappling? Have biologists been proposing theories that violate physics, and they didn’t tell me?

The citations to back up that outré claim are Stuart Kauffman, who can get a little weird but not that weird, and Ryan Gregory, whose papers I’ve used in class, and is probably a bit annoyed at being told his work supports that ridiculous claim.

These laws underpin life’s origin, evolution and the development of human culture and technology, yet they do not predict the emergence of these phenomena.

Sure. Emergent properties exist. We know you can’t simply derive all of biology from Ideal Gas Law. So far, nothing new.

Evolutionary theory explains why some things exist and others do not through the lens of selection.

Uh-oh. Just selection? Tell me you know nothing of evolutionary biology without saying you don’t know anything about evolutionary biology.

To comprehend how diverse, open-ended forms can emerge from physics without an inherent design blueprint, a new approach to understanding and quantifying selection is necessary3,4,5.

Here it comes, more bad theorizing. It is implicit in evolution that there is no “inherent design blueprint,” so where did these authors get the idea that design was a reasonable alternative? They don’t say. This is simply another imaginary controversy they’ve invented to make their theory look more powerful.

We don’t need a "new approach" to selection. To support that, they cite Charles Darwin (???) and Sean B. Carroll, and a fellow named Steven Frank, whose work I’m unfamiliar with. A quick search shows that he applies “evolutionary principles to the biochemistry of microbial metabolism,” which doesn’t sound foreign to standard biology, although he does throw the word “design” around a lot.

But here we go:

We present assembly theory (AT) as a framework that does not alter the laws of physics, but redefines the concept of an ‘object’ on which these laws act. AT conceptualizes objects not as point particles, but as entities defined by their possible formation histories. This allows objects to show evidence of selection, within well-defined boundaries of individuals or selected units.

Again, what biological theory has ever been proposed that alters the laws of physics? They keep touting this as a key feature of their model, that it doesn’t break physics, but no credible theory does. This talk of "formation histories" is nothing revolutionary, history and contingency are already important concepts in biology. Are they really going to somehow quantify “assembly”? They’re going to try.

We introduce a measure called assembly (A), capturing the degree of causation required to produce a given ensemble of objects. This approach enables us to incorporate novelty generation and selection into the physics of complex objects. It explains how these objects can be characterized through a forward dynamical process considering their assembly.

I’ve heard this all before, somewhere. A new term invented, a claim of a novel measure of the complexity of a pathway, a shiny new parameter with no clue how to actually measure it? This is just ontogenetic depth! Paul Nelson should be proud that his bad idea has now been enshrined in the pages of Nature, under a new label. I did a quick check: Nelson is not cited in the paper. Sorry, Paul.

Here is all "assembly theory" is: You count the number of steps it takes to build an organic something, and presto, you’ve got a number "A" that tells you how difficult it was to evolve that something. That’s it. Biology is revolutionized and reconciled with physics. It’s just that stupid.

Read more: https://freethoughtblogs.com/pharyn...elabeled-nothing-more-and-is-just-as-useless/

“ These laws underpin life’s origin, evolution and the development of human culture and technology, yet they do not predict the emergence of these phenomena.”

In this one sentence you’ve just demonstrated your ignorance of evolutionary theory. It is not the purpose or function of evolutionary theory to predict the emergence of these phenomena. It is evolutionary theory purpose to model speciation and the mechanisms by which speciation occurs. I appreciate your thoughtful response but you made it quit clear you don’t understand evolutionary theory.
 
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