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STUDY: TRUMP pushed a drug & 'coereced' testing that caused potential & MAJOR HARM!!
LET US NOT FORGET THE BIG PICTURE HERE. We and the world spent 2 - 2 1/2 months going down TRUMP'S rabbit hole. MORE TIME LOST!
Day 2 after Trump started TOUTING his snake oil theory, this amateur posted the contraindications of his CHOSEN drug right out of the PDR. I stated that was a shitload of contraindications on a 60 year old drug and I NOTED at the time people with HEART DISEASE, DIABETES and alcoholism--active or sober--were major groups which could be precluded from using it. AND that represented a shitload of the US population. My instincts were dead on (no pun intended). Heart arrhythmias lead to sudden heart attacks and STROKES. Surely you have seen the ads. Seems a pretty important 'side effect' to me.
They didn't have the luxury of a double blind study. But HONEST #'s like this don't lie. Of course I guess 6 continents and all the medical institutions could have 'colluded' to change medical records and numbers. Sure! That'll be the next conspiracy theory. Stay tuned...
“It’s one thing not to have benefit, but this shows distinct harm,”
Antimalarial drug touted by President Trump is linked to increased risk of death in coronavirus patients, study says
An analysis of 96,000 patients shows those treated with hydroxychloroquine were also more likely to suffer irregular heart rhythms
By Ariana Eunjung Cha and
Laurie McGinley
May 22, 2020 at 8:28 a.m. EDT
The Washington Post is providing this important information about the coronavirus for free. For more free coverage of the coronavirus pandemic, sign up for our daily Coronavirus Updates newsletter where all stories are free to read.
A study of 96,000 hospitalized coronavirus patients on six continents found that those who received an antimalarial drug promoted by President Trump as a “game changer” in the fight against the virus had a significantly higher risk of death compared with those who did not.
People treated with hydroxychloroquine, or the closely related drug chloroquine, were also more likely to develop a type of irregular heart rhythm, or arrhythmia, that can lead to sudden cardiac death, it concluded.
The study, published Friday in the medical journal the Lancet, is the largest analysis to date of the risks and benefits of treating covid-19 patients with antimalarial drugs. It is based on a retrospective analysis of medical records, not a controlled study in which patients are divided randomly into treatment groups — a method considered the gold standard of medicine. But the sheer size of the study was convincing to some scientists.
“It’s one thing not to have benefit, but this shows distinct harm,” said Eric Topol, a cardiologist and director of the Scripps Research Translational Institute. “If there was ever hope for this drug, this is the death of it.”
David Maron, director of preventive cardiology at the Stanford University School of Medicine, said that “these findings provide absolutely no reason for optimism that these drugs might be useful in the prevention or treatment of covid-19.”
Past studies also found scant or no evidence of hydroxychloroquine’s benefit in treating sick patients, while reports mounted of dangerous heart problems associated with its use. As a result, the Food and Drug Administration last month warned against the use of the drug outside hospital settings or clinical trials
The new analysis — by Mandeep Mehra, a Harvard Medical School professor and physician at Brigham and Women’s Hospital, and colleagues at other institutions — included patients with a positive laboratory test for covid-19 who were hospitalized between Dec. 20, 2019, and April 14, 2020, at 671 medical centers worldwide. The mean age was 54 years, and 53 percent were men. Those who were on mechanical ventilators or who received remdesivir, an antiviral drug made by Gilead Sciences that has shown promise in decreasing recovery times, were excluded.
Mehra said in an interview that the widespread use of antimalarials for covid-19 patients was based on the idea of “a desperate disease demands desperate measures," but that we have learned a hard lesson from the experience about the importance of first doing no harm.
In retrospect, Mehra said, using the drugs without systematic testing was “unwise.”
“I wish we had had this information at the outset,” he said, “as there has potentially been harm to patients.”
Nearly 15,000 of the 96,000 patients in the analysis were treated with hydroxychloroquine or chloroquine alone or in combination with a type of antibiotics known as a macrolide, such as azithromycin or clarithromycin, within 48 hours of their diagnosis.
The difference between patients who received the antimalarials and those who did not was striking.
For those given hydroxychloroquine, there was a 34 percent increase in risk of mortality and a 137 percent increased risk of a serious heart arrhythmias. For those receiving hydroxychloroquine and an antibiotic — the cocktail endorsed by Trump — there was a 45 percent increased risk of death and a 411 percent increased risk of serious heart arrhythmias...
https://www.washingtonpost.com/health/2020/05/22/hydroxychloroquine-coronavirus-study/
LET US NOT FORGET THE BIG PICTURE HERE. We and the world spent 2 - 2 1/2 months going down TRUMP'S rabbit hole. MORE TIME LOST!
Day 2 after Trump started TOUTING his snake oil theory, this amateur posted the contraindications of his CHOSEN drug right out of the PDR. I stated that was a shitload of contraindications on a 60 year old drug and I NOTED at the time people with HEART DISEASE, DIABETES and alcoholism--active or sober--were major groups which could be precluded from using it. AND that represented a shitload of the US population. My instincts were dead on (no pun intended). Heart arrhythmias lead to sudden heart attacks and STROKES. Surely you have seen the ads. Seems a pretty important 'side effect' to me.
They didn't have the luxury of a double blind study. But HONEST #'s like this don't lie. Of course I guess 6 continents and all the medical institutions could have 'colluded' to change medical records and numbers. Sure! That'll be the next conspiracy theory. Stay tuned...
“It’s one thing not to have benefit, but this shows distinct harm,”
Antimalarial drug touted by President Trump is linked to increased risk of death in coronavirus patients, study says
An analysis of 96,000 patients shows those treated with hydroxychloroquine were also more likely to suffer irregular heart rhythms
President Trump on May 18 said that he has been taking the anti-malarial drug hydroxychloroquine as a preventive measure against the coronavirus. (The Washington Post)
By Ariana Eunjung Cha and
Laurie McGinley
May 22, 2020 at 8:28 a.m. EDT
The Washington Post is providing this important information about the coronavirus for free. For more free coverage of the coronavirus pandemic, sign up for our daily Coronavirus Updates newsletter where all stories are free to read.
A study of 96,000 hospitalized coronavirus patients on six continents found that those who received an antimalarial drug promoted by President Trump as a “game changer” in the fight against the virus had a significantly higher risk of death compared with those who did not.
People treated with hydroxychloroquine, or the closely related drug chloroquine, were also more likely to develop a type of irregular heart rhythm, or arrhythmia, that can lead to sudden cardiac death, it concluded.
The study, published Friday in the medical journal the Lancet, is the largest analysis to date of the risks and benefits of treating covid-19 patients with antimalarial drugs. It is based on a retrospective analysis of medical records, not a controlled study in which patients are divided randomly into treatment groups — a method considered the gold standard of medicine. But the sheer size of the study was convincing to some scientists.
“It’s one thing not to have benefit, but this shows distinct harm,” said Eric Topol, a cardiologist and director of the Scripps Research Translational Institute. “If there was ever hope for this drug, this is the death of it.”
David Maron, director of preventive cardiology at the Stanford University School of Medicine, said that “these findings provide absolutely no reason for optimism that these drugs might be useful in the prevention or treatment of covid-19.”
Past studies also found scant or no evidence of hydroxychloroquine’s benefit in treating sick patients, while reports mounted of dangerous heart problems associated with its use. As a result, the Food and Drug Administration last month warned against the use of the drug outside hospital settings or clinical trials
The new analysis — by Mandeep Mehra, a Harvard Medical School professor and physician at Brigham and Women’s Hospital, and colleagues at other institutions — included patients with a positive laboratory test for covid-19 who were hospitalized between Dec. 20, 2019, and April 14, 2020, at 671 medical centers worldwide. The mean age was 54 years, and 53 percent were men. Those who were on mechanical ventilators or who received remdesivir, an antiviral drug made by Gilead Sciences that has shown promise in decreasing recovery times, were excluded.
Mehra said in an interview that the widespread use of antimalarials for covid-19 patients was based on the idea of “a desperate disease demands desperate measures," but that we have learned a hard lesson from the experience about the importance of first doing no harm.
In retrospect, Mehra said, using the drugs without systematic testing was “unwise.”
“I wish we had had this information at the outset,” he said, “as there has potentially been harm to patients.”
Nearly 15,000 of the 96,000 patients in the analysis were treated with hydroxychloroquine or chloroquine alone or in combination with a type of antibiotics known as a macrolide, such as azithromycin or clarithromycin, within 48 hours of their diagnosis.
The difference between patients who received the antimalarials and those who did not was striking.
For those given hydroxychloroquine, there was a 34 percent increase in risk of mortality and a 137 percent increased risk of a serious heart arrhythmias. For those receiving hydroxychloroquine and an antibiotic — the cocktail endorsed by Trump — there was a 45 percent increased risk of death and a 411 percent increased risk of serious heart arrhythmias...
https://www.washingtonpost.com/health/2020/05/22/hydroxychloroquine-coronavirus-study/
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