I think the oppression of the Jews in Europe was for reasons more related to socio-economics, politics, xenophobia, culture, rather than strictly religious reasons. With very few exceptions, the popes and leaders of the Medieval church wrote that Jews weren't entitled to the same rights as christians, but they shouldn't be harassed or assaulted.
I just finished my audio book on Jewish civilization from late antiquity to the early modern era.
The experience and history of the Jewish diaspora is a lot more complex than I imagined.
Up until the late Middle Ages, Christian western Europe was generally semi-tolerant of the Jews. The doctrine articulated by Saint Augustine was that Jews might be second class citizens, but they should not be harassed, forcibly converted, or assaulted. It was the job of Jesus to convert them upon his return. It wasn't the job of Europeans to convert them.
The crusades and economic factors in the High and Late Middle Ages manifested in resentment towards the Jews, and that was the beginning of widespread harassment of the Jews. That is why a lot of Jews went to Eastern Europe, in the early modern period there were more economic opportunities and less harassment in the Polish commonwealth.
Interestingly, when the Jews were expelled from Spain in 1492, a lot of them went to the Ottoman empire, because the Ottoman Muslims were generally tolerant and welcoming to Jews; it didn't hurt that the Jews had a lot of skills the Ottomans valued.
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