Depends on the state. In many deep blue states you have no right to self defense
The Ohio Legislature has just passed a bill that would move Ohio from "duty to retreat" to "stand your ground"; it's now in front of Gov. DeWine for
reason.com
Many states allow a person to stand their ground and use deadly force in self-defense, while some states still impose a duty to retreat in most locations.
www.justia.com
In many deep blue states, say like Massachusetts, you have to retreat if possible and can only use force if you've exhausted all other options and have no path to retreat. Deadly force is never considered an alternative that you can use without massive justification. The state is likely to charge you with felonies for using it.