I like that venn diagramAgreed. It's called "growing up". Maturing into an adult. If they can't do that, then they need to seek help to resolve their issues.
Agreed on the difference between physical matters and spiritual ones. In this case, as stated previously, the problem is mental. It's blocking them from growing. The psychological trauma of childhood experiences prevents them from becoming a fully actualized adult. As you mentioned, most people grow out of it.
OTOH, it's possible they are suffering from a genetic defect that prevents them from experiencing their spiritual nature, much like a color-blind person can't see certain colors.
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Even Einstein knew that the answers to life, the universe, and everything wasn't simply found by burying your head in a science textbook and placing science on a pedestal of worship.

