No.
The concept of un/inalienable rights is pointless unless a people are coming together to form a system of governance based on specific foundational premises.
a) all governmental power is derived from the people.
b) government possesses only the limited powers expressly conferred (surrendered) to it, by the people.
c) there exist certain powers over one's self that are too important to ever be surrendered to the care or control of another person (un/inalienable rights)
d) no legitimate government (one established to protect the rights of the people) would accept the surrender of those rights even if it was offered.
e) government only exercises those limited powers with the consent of the people.
f) if the government ever exceeds the power granted to it, the people retain the right to rescind that consent to be governed, reclaim the powers originally granted to government and unseat the usurpers (with violence if necessary).
When one is arguing against the "existence" of inalienable rights you should remember that when the concept was introduced, it stood in opposition to the system of governance based on a King's unquestionable, "divine right" to rule over his subjects . . . And we won.
I find it amusing that those arguing today against the fundamental principles of the COTUS are usually adherents to communitarian / collectivist ideals, which wouldn't make their appearance for 200 or so more years.
IOW, Marx wasn't a founding father.