First, the Jury can decide that what Cohen said about the Checks was true, that even though he is a huge liar on many issues, for whatever reason they believe him about what Donald Trump knew about the checks and if they believe that he is Guilty.
Second, they can totally disregard Cohen and believe that all the other evidence about Trump and how he ran his business and how he micromanaged everything and how he operated, added to the clear motivation to precent Daniels from saying what ever she was going to say (regardless of truth) he knew. Granted this is circumstantial evidence, but a jury is allowed to convict on circumstantial evidence, it is done every day.
Third, they can believe a combination of the evidence, in this scenario they can believe that Cohen is a liar, but that because of all the circumstantial evidence about the situation and how Trump ran his business they believe that Cohen's testimony leaves no reasonable doubt that he was telling the truth.
I am not saying all jurors will see these scenarios as proven beyond a reasonable doubt and thus that Trump will be convicted, but I believe it is very possible.
I would be shocked if they all believe the case was not proven beyond a reasonable doubt and thus they will exonerate him.
I would be surprised if the Prosecution does not outline these possibilities for the jury.
(Cue the unrelated personal attacks from those who are triggered by this post)